Incidence of Cervical Cancer in Women in the United States 2001 to 2019 & More Trending News

 

Posted: 12/1/2022 10:05:00 AM

Last Updated: 12/1/2022 11:54:14 AM

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In a examine reported as a analysis letter in JAMA, Shahmoradi et al discovered that the incidence of cervical most cancers decreased or remained steady in U.S. girls between 2001 and 2019, apart from a rise in the 30- to 34-year-old age group in newer years.

As said by the investigators, “A recent U.S. study reported that previously declining cervical cancer incidence has plateaued between 2012 and 2017. A significant reduction in cervical cancer screening uptake and adherence to guidelines-concordant recommendations has also been reported, particularly among women aged 21 to 29 years. We evaluated calendar trends in cervical cancer incidence by age at diagnosis.”

Study Details

The examine concerned knowledge from the 2001–2019 National Program of Cancer Registries and Surveillance, Epidemiology, and End Results knowledge set. Annual proportion adjustments (APCs) in incidence of hysterectomy-corrected cervical most cancers had been analyzed by 5-year age teams and for ladies aged < 24 years and ≥ 85 years; analyses confirmed change from 2001 to 2019 alone for some age teams and for 2 to three intervals throughout the examine interval for others.  

Key Findings

During 2001 to 2019, 227,062 instances of cervical most cancers had been reported. Overall, hysterectomy-corrected cervical most cancers incidence decreased from 12.39 instances/100,000 person-years in 2001 to 9.80/100,000 person-years in 2019 (APC = −1.2%, 95% confidence interval [CI] = −1.6% to −0.9%).

Reductions in incidence had been noticed for the youngest (< 24 years) and oldest (≥ 55 years) age teams, with incidence being comparatively steady in latest years amongst girls aged 35 to 54 years. Annual proportion adjustments had been damaging for all age teams from 2001 to 2019 or for intervals throughout this era—besides for ladies aged 30 to 34 years throughout 2012 to 2019.       

Among girls aged 30 to 34 years, a decline in incidence from 12.77/100, 000 to 10.14/100,000 person-years (APC = −2.3%, 95% CI = −2.8% to −1.7%) from 2001 to 2012 was adopted by a rise from 2012 to 2019 reaching 11.60/100,000 person-years in 2019 (APC = +2.5%, 95% CI = +1.4% to +3.6%).

During 2012 to 2019, incidence in the 30- to 34-year-old age group elevated amongst Hispanic girls (APC = +3.0%, 95% CI = +0.3% to +5.7%), non-Hispanic White girls (APC = +2.8%, 95% CI = +0.6% to +5.0%), and ladies of different race/ethnicity (APC = 5.0%, 95% CI = +2.7% to +7.4%), with no obvious improve amongst Black girls (APC = −0.8%, 95% CI = −2.8% to +1.2%). Increases had been noticed for localized (APC = +2.8%, 95% CI = +1.3% to +4.3%) and regional illness (APC = +1.9%, 95% CI = +0.7% to +3.1%) in addition to for squamous cell carcinoma (APC = +2.6%, 95% CI = +1.0% to +4.2%) and adenocarcinoma (APC = +3.0%, 95% CI = +0.9% to +5.1%).

The investigators said, “Between 2001 and 2019, cervical cancer incidence declined or remained stable among U.S. women except for the 30- to 34-year-old age group, in whom incidence increased 2.5% per year after 2012. The observed increase in incidence among 30- to 34-year-old women could be real as a result of a true increase in cervical cancer incidence or due to increased early detection with a stable disease occurrence. If the increase is real, it could be a result of missed screening opportunities at earlier ages, as suggested by the increase in squamous cell carcinoma and localized disease.”

Ashish A. Deshmukh, PhD, MPH, of the Department of Public Health Sciences, Hollings Cancer Center, Medical University of South Carolina, Charleston, is the corresponding writer for the JAMA article.

Disclosure: The examine was supported by grants from the National Cancer Institute and National Institute on Minority Health and Health Disparities. For full disclosures of the examine authors, go to jamanetwork.com.

 

The content material in this submit has not been reviewed by the American Society of Clinical Oncology, Inc. (ASCO®) and doesn’t essentially replicate the concepts and opinions of ASCO®.


Incidence of Cervical Cancer in Women in the United States 2001 to 2019

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Incidence of Cervical Cancer in Women in the United States 2001 to 2019

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Incidence of Cervical Cancer in Women in the United States 2001 to 2019

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